I think i enjoyed this game in the best possible order (illiterate, spastic, crippled, near blind), and while i see that the random nature of disability goes with the random choice, i would personally consider making it ordered.
Especially being illiterate makes a much bigger impression if it is the first playthrough, with the unability to read what you actually don't know yet and the sign before the last room telling you the rythm of the platforms ("If i had known that before!!"). Also i was glad that i had crippled inbetween spastic and nearly blind, because those two after another would have been too much for me - and i was glad to have a break with a more emotional emphasis. To say the least, i wouldn't have liked this game so much if i would have started spastic or near blind. But as it went, i really like it.